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DOI: 10.1055/s-2006-960954
© Georg Thieme Verlag Stuttgart · New York
Glaucolide B, A Molluscicidal Sesquiterpene Lactone, and Other Constituents of Vernonia eremophila
Publication History
1989
Publication Date:
05 January 2007 (online)

Abstract
The sesquiterpene lactone glaucolide B was isolated from the molluscicidal extract of Vernonia eremophila Mart, and shown to be responsible for the molluscicidal activity. Hydrogenolysis of glaucolide B resulted in the disappearance of the activity. Other inactive constituents of the extract were 3,7-dimethoxy-5,3′,4′-trihydroxyflavone and two transformation products, possibly artefacts, of glaucolide B. Glaucolide B exhibited strong antimicrobial activity against B, cereus and moderate activity against S. aurens, but was inactive in several other systems.
Key words
Vernonia eremophylla - glaucolides - sesquiterpene lactones - molluscicides - flavonoids